Description
A plant-derived ester of a sesquiterpenic alcohol that acts as an agonist for ERα (IC50 = 33.1 nM) and an agonist/antagonist for ERβ (IC50 = 180.5 nM); demonstrates ionophorectic properties, increasing calcium permeability of lipid bilayer membranes, mitochondria, thymocytes, sarcoplasmic reticulum, and liposomes at 1-50 µM